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Abstract
Background: Appendicitis is a surgical emergency
and surgery is crucial for patients diagnosed with
having acute appendicitis as any delay in surgery
leads to perforation of the organ
Methods: 50 Patients with provisional diagnosis of
acute appendicitis were included in the study. Preoperative blood sample was analysed for neutrophil
percentage. The patients were divided into two
groups, each comprising of 25 patients on the basis
of neutrophil percentage i.e. group A having
neutrophils ≥ 75% and group B having neutrophils ≤
75%. Patients were then followed-up and peroperative findings and histopathology reports were
noted for differentiating between perforated and
inflamed appendices. SPSS version 22.0 was used
for analysis and Pearson’s Chi square test was
applied at 5% level of significance. Relative risks
along with 95% confidence intervals were also
calculated.
Results: 15/25 (60%) patients in Group A developed
perforation of appendix when compared to only 1/25
(4%) patient in Group B, who later developed
perforation (Relative risk = 15.0, 95% confidence
interval=2.1408 to 105.10, P value=0.00). No
statistically significant association was observed
between age and gender with perforation of
appendix.
Conclusion: There is a highly significant statistical
association of shift to the left of neutrophils with
perforation of appendix.
Key Words: Shift to the left of neutrophils,
perforated appendix.